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ICU Primary Exam
Vivian Imbriotis
These are my primary exam notes. They have
not
been vetted and are
not
useful.
Pharmacology
One compartment model
Multicompartment model
Absorption, first pass, and bioavailability
Drug metabolism, elimination, excretion
Receptor theory
Mechanisms of drug effect
Dose-response relationships
Adverse drug reactions
Drug-drug interactions
Tolerance and tachyphylaxis
Cells
Organelles
Membrane voltage
Transport across membranes
Respiratory
Respiratory anatomy
Mechanics of breathing
Volumes and capacities
Respiratory compliance
Respiratory resistance
The pulmonary circulation
Pulmonary vascular resistance
Regional variation in ventilation and perfusion
Work of breathing
Diffusion of respiratory gasses
Carriage of gasses in the blood
Oxygen and CO2 cascade
Control of breathing
Neonatal respiratory physiology
Non-ventilatory functions of the lungs
Compostion and function of surfactant
Cardiovascular
Cardiac Functional Anatomy
The coronary circulation
Electrical properties of the heart
Determinants of cardiac output
The cardiac cycle, CVP, arterial waveforms
The peripheral circulation
Blood pressure and the cardiac reflexes
Special peripheral circulations
Applied cardiovascular physiology
Renal, body fluids, electrolytes
Renal structure and function
Renal blood flow and GFR
Countercurrent mechanisms and ADH
Consequences of chronic renal failure
Osmosis and starling forces
The body fluid
Renal handling of water and solute
Physical mechanisms of haemodialysis
Lymph
Role, distribution and regulation of ions
IV fluid therapy
Acid-Base
Stewart approach
Renal handling of an acid load
Buffers
Neurology
The autonomic nervous system
Cranial nerve reflex arcs
Major somatosenosory pathways
Classification of nerve fibers
The blood-brain barrier
Production, function, and composition of CSF
Determinants of intracranial pressure
Physiology of pain
Seizures and anticonvulsants
Opioids
Sedatives
Neuromuscular blockers
Antipsychotics
Antimuscarinics
Local anaesthetics
Paracetamol and N-acetylcysteine
Gastrointestinal, nutrition, metabolism
Gastrointestinal blood supply
GI secretions
Absorption of nutrients
GI motility
Hepatic physiology
Hepatic functional anatomy
Vomiting
Pancreatic exocrine function
Bile
Hormonal response to a meal
Handling of ammonia
Laboratory assessment of hepatic function
Daily nutritional requirements
Basal metabolic rate
Energy stores and starvation
Protein metabolism
Ketones and lactate
Dose, composition, and side effects of feeds
Haematology
Coagulation
Red blood cells
The platelets
Physiological effects of isolvolaemic anaemia
Anticoagulants
Measures of clotting function
Antiplatelet agents
Blood grouping and matching
Adverse effects of transfusion
Immunology and microbiology
Innate immunity and compliment
The adaptive immune system
Hypersensitivity
Classification of bacteria
Antibiotics
Mechanisms of antimicrobial resistance
Fungus and antifungals
Viruses and antivirals
Endocrinology
Regulation of calcium
Control of blood glucose
Thyroid hormones
Structure and function of the hypothalamus
The anterior pituitary gland
Obestetrics
Physiology of the placenta
Maternal physiology of labor
Maternal cardiovascular physiology of pregnancy
Maternal respiratory physiology of pregnancy
Measurement and equipment
Pulse oximetry and cooximetry
Resonance and damping in arterial lines
Cardiac output monitoring
Capnography
Principles of medical ultrasound
Sadly, anatomy
Anatomy of vessels for line insertion
Anatomy relevant to airway procedures and ICCs
Anatomy relevant to lumbar puncture