Adverse drug reactions

An adverse drug reaction is a reaction where

• The reaction is directly related to the drug
• The drug was being used correctly and appropriately
• The reaction is harmful

Type A: Augmented dose-related adverse effects (hypotension from antihypertensives)

Type B: Bizarre dose-independant adverse effects (anaphylaxis)

Type C: Chronic Dose- and Time-related (HPA axis suppression)

Type D: Delayed Time- related effects (tardive dyskinesia)

Type E: End-of-use withdrawal effects

Type F: Failure of therapy (antibiotic resistance, ECMO adsorbtion, plasmapheresis removal).