Chief cell \(\to\) pepsinogen release (also directly stimulated by ACh)
Parietal cell \(\to\) HCl release
Antrum \(\to \ \uparrow\)contraction strength and frequency \(\to \ \uparrow\)gastric emptying
Intestinal phase
\(\downarrow\)pH in duodenum (requires alkalinization before accepting more material from stomach) \(\to\) S-cell \(\to\) secretin release \(\to \ \uparrow\)alkaline pancreatic juice secretion, delayed gastric emptying
Proteins and fats in duodenum \(\to\) I-cell \(\to\) CCK release \(\to\) GRID - gallbladder contracts, sphincter of oddi relaxes, increased pancreatic secretions, delayed gastric emptying
Once pH rises (duodenum ready for current chyme to leave and to accept more from stomach) \(\to\) Mo-cell \(\to\) motilin release \(\to\) increased gastric emptying, increased intestinal motility
As nutrients travel to jejunum and ileum \(\to\) GLP1 release \(\to\) satiety, \(\downarrow\)gastric emptying, insulin release potentiated